Firefly Bio

Scientist / Senior Scientist – In Vivo & In Vitro Pharmacology, Oncology

SOUTH SAN FRANCISCO, CAPosted 30+ days ago

Job summary

  • Job post source

    This job is directly from Firefly Bio

  • Job overview

    The Scientist/Senior Scientist in In Vivo & In Vitro Pharmacology at Firefly Bio focuses on oncology drug discovery, particularly antibody-drug conjugates, contributing to preclinical development and advancing the therapeutic pipeline.

  • Responsibilities and impact

    The role involves designing and executing in vivo tumor model studies, developing in vitro pharmacology assays, analyzing biomarker data, managing animal studies, ensuring regulatory compliance, collaborating with cross-functional teams, presenting data, and mentoring junior scientists.

  • Experience and skills

    Candidates need a PhD with 5+ years or MS with 6+ years in relevant industry experience, expertise in in vivo pharmacology techniques, in vitro assay design, ADC biology, and familiarity with regulatory documentation; strong communication and leadership skills are essential.

  • Work environment and culture

    The position requires working independently in a fast-paced, cross-functional team environment with flexibility for some weekend work, fostering scientific excellence and innovation.

  • Company information

    Firefly Bio is a biopharmaceutical company specializing in oncology drug discovery, focusing on antibody-drug conjugates and preclinical therapeutic development.

  • Team overview

    The candidate will join the in vivo and in vitro pharmacology team, collaborating closely with chemistry, biology, bioanalytical, and translational teams.

  • Unique job features

    This role offers a unique opportunity to work on cutting-edge oncology therapeutics with a focus on ADCs, involving both in vivo and in vitro pharmacology and biomarker assay development.

Company overview

Firefly Bio is a biotechnology company specializing in the development of innovative gene therapies aimed at treating rare genetic disorders. They generate revenue through the research, development, and commercialization of these therapies, often partnering with pharmaceutical companies and research institutions. Founded in 2015, Firefly Bio has made significant strides in gene editing technologies, particularly with their proprietary CRISPR-based platforms, positioning themselves as leaders in the biotech industry. Their mission is to transform the lives of patients with previously untreatable conditions, driving advancements in personalized medicine.

How to land this job

  • Tailor your resume to emphasize your expertise in in vivo pharmacology, particularly your experience with mouse oncology models such as CDX, PDX, and GEMMs, and highlight your skills in designing and executing efficacy, PK/PD, and biomarker studies relevant to antibody-drug conjugates (ADCs).

  • Showcase your proficiency in in vitro pharmacology assays including ELISA, flow cytometry, qPCR, Western blotting, and IHC, and your ability to synthesize complex pharmacology and biomarker data to provide strategic insights that drive drug discovery programs forward.

  • Apply through multiple platforms including Firefly Bio's corporate career site and LinkedIn to maximize your exposure and ensure your application is seen by multiple recruiters or hiring managers.

  • Connect with current Firefly Bio employees in the pharmacology or oncology divisions on LinkedIn to gain insider insights and demonstrate genuine interest; consider opening conversations with ice breakers like commenting on recent Firefly Bio oncology research publications or asking about their experience working on ADC projects.

  • Optimize your resume for ATS by incorporating key terms from the job description such as 'in vivo pharmacology,' 'tumor models,' 'ADC mechanism of action,' 'biomarker assay development,' and 'PK/PD studies' to increase your chances of passing automated screening.

  • Utilize Jennie Johnson's Power Apply feature to automate tailored applications across multiple platforms, identify relevant Firefly Bio contacts for networking, and optimize your resume for ATS, allowing you to focus your time on interview preparation and skill enhancement.

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