Job summary
Job post source
This job is directly from Engage Bio
Job overview
The Scientist - Genetic Medicine R&D role at Engage Bio involves supporting preclinical research to optimize and produce Tethosome nucleic acids, contributing broadly to molecular biology and platform development in early-stage biotech R&D.
Responsibilities and impact
The candidate will lead optimization and purification of Tethosome nucleic acids, develop chromatographic workflows, design molecular biology experiments, deliver data packages, develop assays, and collaborate across functions to support R&D projects.
Compensation and benefits
The position offers a base salary of $100-130,000 depending on experience, significant equity compensation, performance-based bonuses, and full health, dental, and vision insurance.
Experience and skills
Candidates should have a PhD in Molecular Biology or related field, with hands-on experience in chromatographic nucleic acid purification preferred; strong generalist molecular biology skills and adaptability are valued.
Career development
The role provides broad exposure to early-stage biotech R&D projects from concept to IND-enabling studies, offering opportunities to grow with an ambitious company and contribute to high-impact science.
Work environment and culture
Engage Bio offers a fast-paced, mission-driven environment with a dynamic biotech community, state-of-the-art lab facilities, team events, and a collaborative culture focused on innovation.
Company information
Engage Bio is an early-stage biotech company pioneering genetic medicine with its proprietary Tethosome platform that enhances DNA therapy expression and reduces toxicity, targeting rare and common diseases.
Team overview
The candidate will join the R&D team working cross-functionally on platform innovation and preclinical research, collaborating with diverse specialists in a dynamic setting.
Job location and travel
The job is full-time, on-site at MBC Biolabs in San Carlos, featuring modern lab facilities and a collaborative community environment.
Application process
Applicants are encouraged to submit a cover letter detailing relevant experience, particularly in molecular cloning, cell culture, assay development, and cross-disciplinary collaboration.
Unique job features
Unique aspects include working with the proprietary Tethosome platform, opportunities to impact early-stage genetic medicine development, and access to cutting-edge scientific instruments in a vibrant biotech incubator.
Company overview
Engage Bio is a biotechnology company based in San Carlos, California, specializing in the development of mRNA therapies aimed at transforming cancer cells into factories for locally acting immunotherapies. Founded in 2021 by Kathryn Kwant and Will Olsen, the company is backed by Y Combinator and focuses on innovative cancer treatments. Engage Bio's platform technology leverages messenger Ribonucleic Acid (mRNA) to create potent, safe, and programmable genetic medicines, positioning itself as a pioneer in the biotech sector. The company has a small team of five employees and is in the seed stage of development.
How to land this job
Position your resume to highlight your expertise in molecular biology and nucleic acid purification, emphasizing any hands-on experience with chromatographic workflows and optimization of nucleic acids production, as these are central to Engage Bio's Scientist role.
Focus on showcasing your adaptability in fast-paced R&D environments, your ability to collaborate cross-functionally, and your skills in molecular cloning, mammalian cell culture, and assay development to align with the job's broad research scope.
Apply through Engage Bio's official careers page as well as LinkedIn and other biotech job boards to maximize your application visibility and increase your chances of landing an interview.
Connect on LinkedIn with current scientists and R&D team members at Engage Bio, using ice breakers such as commenting on recent company breakthroughs in genetic medicine or asking about their experience working on the Tethosome platform to start meaningful conversations.
Optimize your resume for ATS by incorporating keywords from the job description like 'chromatographic nucleic acid purification,' 'molecular cloning,' 'fast-paced R&D,' and 'assay development' to ensure your resume passes initial automated screenings.
Utilize Jennie Johnson's Power Apply feature to automate tailored applications across multiple platforms and identify relevant LinkedIn contacts, freeing up your time to prepare thoroughly for interviews and deepen your industry research.
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